Structure-based design, synthesis, and profiling of potent and selective neuronal nitric oxide synthase (nNOS) inhibitors with an amidinothiophene hydroxypiperidine scaffold-Reference-Cited by-同舟云学术

Structure-based design, synthesis, and profiling of potent and selective neuronal nitric oxide synthase (nNOS) inhibitors with an amidinothiophene hydroxypiperidine scaffold

Published:2011 Issue:3 Volume:2 Page:201
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Liang Guyan,Neuenschwander Kent,Chen Xin,Wei Linli,Munson Randall,Francisco Gerardo,Scotese Anthony,Shutske Gregory,Black Mark,Sarhan Sharkir,Jiang Jason,Morize Isabelle,Vaz Roy J.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2011/MD/C0MD00255K

Reference38 articles.

1. Cerebral Blood Flow Regulation by Nitric Oxide: Recent Advances

2. Nitric Oxide: Role in Biological System

3. Role of Nitric Oxide Synthases in Parkinson’s Disease: A Review on the Antioxidant and Anti-inflammatory Activity of Polyphenols

4. Nitric Oxide and Nitroxidative Stress in Alzheimer's Disease

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5. Accessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase Inhibitors;ACS Medicinal Chemistry Letters;2013-11-11