Co-delivery of proanthocyanidin and mitoxantrone induces synergistic immunogenic cell death to potentiate cancer immunotherapy-Reference-Cited by-同舟云学术

Co-delivery of proanthocyanidin and mitoxantrone induces synergistic immunogenic cell death to potentiate cancer immunotherapy

Published:2022 Issue:16 Volume:10 Page:4549-4560
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Qian Ying¹,Mao Jiarong²,Leng Xuejiao¹,Zhu Ling¹,Rui Xue¹,Jin Zhetong¹,Jiang Houzhe¹,Liu Heng¹³,Zhang Fengguang¹,Bi Xiaolin¹,Chen Zhipeng¹,Wang Jingjing¹^ORCID

Affiliation:

1. College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China

2. The First Clinical Hospital of Nanjing University of Chinese Medicine, Nanjing, 210023, China

3. Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali 671000, China

Abstract

Tumor microenvironment-responsive nanoparticles self-assembled from polypeptide checkpoint inhibitor polymer, mitoxantrone and proanthocyanidins can reprogram the tumor microenvironment and improve the efficacy of colorectal cancer immunotherapy.

Funder

National Natural Science Foundation of China

Nanjing University of Chinese Medicine

Natural Science Research of Jiangsu Higher Education Institutions of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00611A

Reference48 articles.

1. Colorectal cancer statistics, 2020