A metal–polyphenolic nanosystem with NIR-II fluorescence-guided combined photothermal therapy and radiotherapy

Author:

Li Jie12,Li Wenxi12,Xie Lisi12,Sang Wei12,Wang Guohao12,Zhang Zhan12,Li Bei12,Tian Hao12,Yan Jie12,Tian Ye12,Li Zhenhua3ORCID,Fan Quli4ORCID,Yu Lin5ORCID,Dai Yunlu12ORCID

Affiliation:

1. Cancer Centre and Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau SAR 999078, China

2. MoE Frontiers Science Center for Precision Oncology, University of Macau, Macau SAR 999078, China

3. Affiliated Dongguan Hospital, Southern Medical University, Dongguan 523059, China

4. Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications, Nanjing 210023, China

5. State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200438, China

Abstract

A polyphenolic semiconducting polymer was prepared to chelate the high-Z Hf ions, followed by coating of the amphiphilic polymers to form a nanostructure (CPPDA–Hf@Poloxamer nanoparticles) for precise lesion imaging and photothermal therapy.

Funder

Universidade de Macau

Science and Technology Development Fund

Shenzhen Science and Technology Innovation Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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