Aspartame and sucralose extend the lifespan and improve the health status of C. elegans-Reference-Cited by-同舟云学术

Aspartame and sucralose extend the lifespan and improve the health status of C. elegans

Published:2021 Issue:20 Volume:12 Page:9912-9921
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhang Mohan¹²^ORCID,Chen Shuai¹,Dai Yuhua³,Duan Ting²,Xu Yuying²,Li Xiaolin⁴,Yang Jun⁵⁶^ORCID,Zhu Xinqiang³²

Affiliation:

1. Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang 325000, China

2. Department of Toxicology, Zhejiang University School of Public Health, Hangzhou, Zhejiang 310058, China

3. The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang 322000, China

4. Technical Center for Animal, Plant and Food Inspection and Quarantine of Shanghai Customs district, Shanghai 200135, China

5. Department of Toxicology, Hangzhou Normal University School of Medicine, Hangzhou, Zhejiang 311121, China

6. Zhejiang Provincial Center for Uterine Cancer Diagnosis and Therapy Research, The Affiliated Women's Hospital, Zhejiang University, Hangzhou, Zhejiang 310006, China

Abstract

Aspartame and sucralose increased the lifespan, reduced lipofuscin accumulation, and transiently increased motility in C. elegans, and we hypothesized that the hormesis effect might be the underlying mechanism.

Funder

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO01579F

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