The flexibility–complementarity dichotomy in receptor–ligand interactions
Author:
Affiliation:
1. Department of Chemistry
2. University of Sheffield
3. Sheffield S3 7HF
4. UK
Abstract
Binding affinity does not increase uniformly with preorganization, because there is a trade off between flexibility and fit.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/SC/C4SC03398A
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