A solid-supported organocatalyst for asymmetric Mannich reaction to construct C2-quaternary indolin-3-ones-Reference-Cited by-同舟云学术

A solid-supported organocatalyst for asymmetric Mannich reaction to construct C2-quaternary indolin-3-ones

Published:2022 Issue:12 Volume:12 Page:7040-7045
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

An Jian-Xiong¹,Yang Fen-Fen¹,Wang Pan¹,Gu Zhi-Cheng¹,Li Yan²,Chen Lei¹,Zhao Yong-Long¹,He Bin¹^ORCID

Affiliation:

1. State Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, Engineering Research Center for the Development and Application of Ethnic Medicine, TCM (Ministry of Education), Guizhou Medical University, Guiyang 550004, People's Republic of China

2. School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, People's Republic of China

Abstract

A simple and novel solid-supported organocatalyst from a 2-chlorotrityl chloride resin-immobilized 4-hydroxyproline was developed, which has been used for the asymmetric Mannich reaction of 2-aryl-3H-indol-3-ones and aldehydes/ketones.

Funder

National Natural Science Foundation of China

Guizhou Science and Technology Department

Guizhou Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA00456A

Reference85 articles.

1. Enantioselective direct aldol reaction: the blossoming of modern organocatalysis