<i>Lactobacillus fermentum</i>F40-4 ameliorates hyperuricemia by modulating the gut microbiota and alleviating inflammation in mice-Reference-Cited by-同舟云学术

Lactobacillus fermentumF40-4 ameliorates hyperuricemia by modulating the gut microbiota and alleviating inflammation in mice

Published:2023 Issue:7 Volume:14 Page:3259-3268
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Cao Jiayuan¹,Wang Ting¹,Liu Yisuo¹,Zhou Wei²,Hao Haining¹,Liu Qiqi¹,Yin Boxing²,Yi Huaxi¹^ORCID

Affiliation:

1. College of Food Science and Engineering, Ocean University of China, Qingdao, 266000, China

2. Yangzhou University Healthy source Dairy Co., LTD., Yangzhou, 225002, China

Abstract

L. fermentumF40-4 could inhibit UA synthetase activity in the liver to decrease UA production, promote expression level of UA excretion transporter NPT1 in the kidney and reshape microbiota in the gut to increase UA excretion, thereby alleviate HUA.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D2FO03701G

Reference45 articles.

1. Uric acid in plants and microorganisms: Biological applications and genetics - A review

2. The Molecular Physiology of Uric Acid Homeostasis

3. From purines to purinergic signalling: molecular functions and human diseases

4. Gout

5. Japanese Guideline for the Management of Hyperuricemia and Gout: Second Edition

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