Synthesis and conversion of primary and secondary 2-aminoestradiols into A-ring-integrated benzoxazolone hybrids and their in vitro anticancer activity-Reference-Cited by-同舟云学术

Synthesis and conversion of primary and secondary 2-aminoestradiols into A-ring-integrated benzoxazolone hybrids and their in vitro anticancer activity

Published:2021 Issue:23 Volume:11 Page:13885-13896
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kovács Ferenc¹²³⁴^ORCID,Gopisetty Mohana K.⁵⁶²⁷⁴,Adamecz Dóra I.⁵⁶²⁷⁴,Kiricsi Mónika⁵⁶²⁷⁴,Enyedy Éva A.⁸⁹²³⁴^ORCID,Frank Éva¹²³⁴^ORCID

Affiliation:

1. Department of Organic Chemistry

2. University of Szeged

3. H-6720 Szeged

4. Hungary

5. Department of Biochemistry and Molecular Biology

6. Doctoral School of Biology

7. H-6726 Szeged

8. Department of Inorganic and Analytical Chemistry

9. Interdisciplinary Excellence Centre

Abstract

Estradiol–benzoxazolone hybrids with a common aromatic moiety were efficiently synthesized via primary and secondary aminophenol intermediates, and their anticancer activities were investigated.

Funder

Nemzeti Kutatási, Fejlesztési és Innovaciós Alap

Emberi Eroforrások Minisztériuma

Ministry for Innovation and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA01889B

Reference47 articles.

1. Natural Product Hybrids as New Leads for Drug Discovery