QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures in the promoter of the S100P gene
Author:
Affiliation:
1. School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK
Abstract
Funder
Biotechnology and Biological Sciences Research Council
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB01464A
Reference34 articles.
1. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
2. G-quadruplexes in promoters throughout the human genome
3. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
4. Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands
5. Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome
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