Dual activity of indolin-2-ones containing an arylidene motif: DNA and BSA interaction-Reference-Cited by-同舟云学术

Dual activity of indolin-2-ones containing an arylidene motif: DNA and BSA interaction

Published:2023 Issue:40 Volume:13 Page:28139-28147
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Bukhari Syed Nasir Abbas¹,Alsahli Tariq G.²,Ejaz Hasan³,Ahmed Naveed⁴,Ahmad Waqas⁵,Elsherif Mervat A.⁶,Alotaibi Nasser H.⁷,Junaid Kashaf⁸,Janković Nenad⁹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Al Jouf, 72388, Saudi Arabia

2. Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Al Jouf, 72388, Saudi Arabia

3. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Al Jouf, 72388, Saudi Arabia

4. Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Al Jouf, 72388, Saudi Arabia

5. Discipline of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor, 11800, Penang, Malaysia

6. Chemistry Department, College of Science, Jouf University, Sakaka, Al Jouf, 72388, Saudi Arabia

7. Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia

8. School of Biological and Behavioural Sciences, Queen Mary University of London, London, E1 4NS, UK

9. University of Kragujevac, Institute for Information of Technologies Kragujevac, Department of Science, Jovana Cvijića bb, 34000 Kragujevac, Serbia

Abstract

The arylidene indolin-2-ones showed significant dual biological activity against MCF-T cancer cell lines and Candida species. The most promising molecule for further investigation contains an m-aminophenyl fragment.

Funder

Al Jouf University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA04997C

Reference58 articles.

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5. Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

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