Flavoenzyme CrmK-mediated substrate recycling in caerulomycin biosynthesis-Reference-Cited by-同舟云学术

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Flavoenzyme CrmK-mediated substrate recycling in caerulomycin biosynthesis

Published:2016 Issue:8 Volume:7 Page:4867-4874
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zhu Yiguang¹²³⁴⁵,Picard Marie-Ève⁶⁷⁸⁹¹⁰,Zhang Qingbo¹²³⁴⁵,Barma Julie⁶⁷⁸⁹¹⁰,Després Xavier Murphy⁶⁷⁸⁹¹⁰,Mei Xiangui¹¹¹²¹³¹⁴¹⁵,Zhang Liping¹²³⁴⁵,Duvignaud Jean-Baptiste⁶⁷⁸⁹¹⁰,Couture Manon⁶⁷⁸⁹¹⁰^ORCID,Zhu Weiming¹¹¹²¹³¹⁴¹⁵,Shi Rong⁶⁷⁸⁹¹⁰,Zhang Changsheng¹²³⁴⁵

Affiliation:

1. CAS Key Laboratory of Tropical Marine Bio-resources and Ecology

2. Guangdong Key Laboratory of Marine Materia Medica

3. South China Sea Institute of Oceanology

4. Chinese Academy of Sciences

5. Guangzhou 510301

6. Département de biochimie

7. de microbiologie et de bio-informatique

8. PROTEO

9. Institut de Biologie Intégrative et des Systèmes (IBIS)

10. Université Laval

11. Key Laboratory of Marine Drugs

12. Chinese Ministry of Education

13. School of Medicine and Pharmacy

14. Ocean University of China

15. Qingdao 266003

Abstract

Biochemical and structural investigations into the flavoenzyme CrmK reveal a substrate recycling/salvaging mechanism in caerulomycin biosynthesis.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Canada Foundation for Innovation

Natural Sciences and Engineering Research Council of Canada

University of Saskatchewan

Western Economic Diversification Canada

National Research Council Canada

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C6SC00771F

Reference51 articles.

1. Microbial NAD Metabolism: Lessons from Comparative Genomics

2. Uracil Salvage Pathway in Lactobacillus plantarum : Transcription and Genetic Studies

3. CbiZ, an amidohydrolase enzyme required for salvaging the coenzyme B12 precursor cobinamide in archaea

4. Biosynthesis of tetrahydrobiopterin by de novo and salvage pathways in adrenal medulla extracts, mammalian cell cultures, and rat brain in vivo.

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3. Structural studies reveal flexible roof of active site responsible for ω-transaminase CrmG overcoming by-product inhibition;Communications Biology;2020-08-19

4. Activation and enhancement of caerulomycin A biosynthesis in marine-derived Actinoalloteichus sp. AHMU CJ021 by combinatorial genome mining strategies;Microbial Cell Factories;2020-08-06

5. The Influence of Caerulomycin A on the Intestinal Microbiota in SD Rats;Marine Drugs;2020-05-22

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