Effect of proteins on the oxidase-like activity of CeO2 nanozymes for immunoassays

Author:

Chen Zi-Jian12345ORCID,Huang Zhicheng56789,Huang Song10114,Zhao Jin-Lin10114,Sun Yuanming1234,Xu Zhen-Lin1234,Liu Juewen56789ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Food Quality and Safety

2. South China Agricultural University

3. Guangzhou 510642

4. China

5. Department of Chemistry

6. Waterloo Institute for Nanotechnology

7. University of Waterloo

8. Waterloo

9. Canada

10. Guangzhou Institute for Food Control

11. Guangzhou 510410

Abstract

Protein adsorption inhibits the oxidase-like activity of CeO2 nanoparticles. Coating a partial shell of silica on CeO2 and subsequent conjugation of antibodies allow highly sensitive and selective detection of fenitrothion.

Funder

Natural Sciences and Engineering Research Council of Canada

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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