Stereospecific recognition and quantitative structure–activity relationship between antibodies and enantiomers: ofloxacin as a model hapten

Author:

Mu Hongtao1234,Wang Baoling1234,Xu Zhenlin1234,Sun Yuanming1234,Huang Xinan5674,Shen Yudong1234,Eremin Sergei A.89101112,Zherdev Anatoly V.891011,Dzantiev Boris B.891011,Lei Hongtao1234

Affiliation:

1. Guangdong Provincial Key Laboratory of Food Quality and Safety

2. South China Agricultural University/Guangdong Provincial Engineering & Technique Research Centre of Food Safety Detection and Risk Assessment

3. Guangzhou 510642

4. China

5. Tropical Medicine Institute

6. Guangzhou University of Chinese Medicine

7. Guangzhou 510405

8. A.N. Bach Institute of Biochemistry

9. Russian Academy of Sciences

10. Moscow 119071

11. Russia

12. Faculty of Chemistry

Abstract

In this study, ofloxacin stereoisomers were chosen as a simple model to investigate the stereospecific recognition of chiral haptens and antibodies.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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