Protein aggregation monitoring in cells under oxidative stress: a novel fluorescent probe based on a 7-azaindole-BODIPY derivative-Reference-Cited by-同舟云学术

Protein aggregation monitoring in cells under oxidative stress: a novel fluorescent probe based on a 7-azaindole-BODIPY derivative

Published:2024 Issue:31 Volume:12 Page:7577-7590
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Herrera-Ochoa Diego¹,Llano Iván²,Ripoll Consuelo¹,Cybulski Pierre³,Kreuzer Martin⁴,Rocha Susana³^ORCID,García-Frutos Eva M.²⁵^ORCID,Bravo Iván¹^ORCID,Garzón-Ruiz Andrés¹^ORCID

Affiliation:

1. Departamento de Química Física, Facultad de Farmacia, Universidad de Castilla-La Mancha, Av. Dr José María Sánchez Ibáñez, s/n, 02071 Albacete, Spain

2. Instituto de Ciencia de Materiales de Madrid (ICMM), CSIC, Cantoblanco, 28049 Madrid, Spain

3. Molecular Imaging and Photonics, Department of Chemistry, KU Leuven, Leuven Chem&Tech, Celestijnenlaan 200F, Leuven, 3001, Belgium

4. ALBA Synchrotron Light Source, Carrer de la Llum 2-26, Cerdanyola del Valles, 08290 Cerdanyola Del Vallès, Barcelona, Spain

5. Departamento de Química Orgánica y Química Inorgánica, Universidad de Alcalá, 28805 Alcalá de Henares, Madrid, Spain

Abstract

The unusual combination of 7-azaindole and BODIPY leads to a multi-emissive fluorescent probe sensitive to protein aggregation in live cells.

Funder

Junta de Comunidades de Castilla-La Mancha

Universitaire Ziekenhuizen Leuven, KU Leuven

HORIZON EUROPE Marie Sklodowska-Curie Actions

Ministerio de Ciencia e Innovación

Universidad de Castilla-La Mancha

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D4TB00567H

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4. Bright solid-state red-emissive BODIPYs: facile synthesis and their high-contrast mechanochromic properties

5. Endogenous CO imaging in bacterial pneumonia with a NIR fluorescent probe