Improving the protein activity and stability under acidic conditions via site-specific conjugation of a pH-responsive polyelectrolyte-Reference-Cited by-同舟云学术

Improving the protein activity and stability under acidic conditions via site-specific conjugation of a pH-responsive polyelectrolyte

Author:

Wang Lei¹²³⁴⁵,Li Xin¹²³⁴⁵,Yuan Lin¹²³⁴⁵,Wang Hongwei¹²³⁴⁵,Chen Hong¹²³⁴⁵,Brash John L.⁶⁷⁸⁹¹⁰

Affiliation:

1. The Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou

2. Department of Polymer Science and Engineering

3. College of Chemistry, Chemical Engineering and Materials Science

4. Soochow University

5. Suzhou

6. School of Biomedical Engineering

7. Department of Chemical Engineering

8. McMaster University

9. Hamilton

10. Canada

Abstract

Site-specific conjugation of pDMAEMA to the protein surface led to a significant increase in protein activity and stability under acidic conditions.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

Reference32 articles.

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