Versatile coordination ability of thioamide ligand in Ru(ii) complexes: synthesis, computational studies, in vitro anticancer activity and apoptosis induction

Author:

Kumar Ramasamy Raj12345ORCID,Ramesh Rengan12345ORCID,Małecki Jan Grzegorz678910ORCID

Affiliation:

1. Centre for Organometallic Chemistry

2. School of Chemistry

3. Bharathidasan University

4. Tiruchirappalli-620 024

5. India

6. Department of Crystallography

7. Institute of Chemistry

8. University of Silesia

9. 40-006 Katowice

10. Poland

Abstract

Two structurally different ruthenium(ii) complexesviadiverse coordination of thioamide ligand have been synthesised and characterized. The complexes exhibit significant cytotoxicity and induce apoptosis in cancer cells.

Funder

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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