Association between ageing, brain chemistry and white matter volume revealed with complementary MRI and FTIR brain imaging-Reference-Cited by-同舟云学术

Association between ageing, brain chemistry and white matter volume revealed with complementary MRI and FTIR brain imaging

Published:2022 Issue:23 Volume:147 Page:5274-5282
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Lam Virginie¹²^ORCID,Phillips Juliette³,Harrild Elizabeth³,Tidy Rebecca J.³,Hollings Ashley L.¹³^ORCID,Codd Lincoln⁴,Richardson Kirsty⁵,Celliers Liesl⁶,Takechi Ryu¹²^ORCID,Mamo John C. L.¹²,Hackett Mark J.¹³^ORCID

Affiliation:

1. Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia

2. School of Population Health, Faculty of Health Sciences, Curtin University, Bentley, WA, Australia

3. School of Molecular and Life Sciences, Faculty of Science and Engineering, Curtin University, Bentley, WA, Australia

4. Harry Perkins Institute of Medical Research, Nedlands, WA, Australia

5. Department of Radiology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia

6. Department of Nuclear Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia

Abstract

Ex vivo FTIR imaging reveals lipid distributions (red) alongside other spectroscopic markers in brain tissue, which can be used to provide greater biochemical insight when combined with in vivo MRI data sets collected from the same brain.

Funder

Australian Institute of Nuclear Science and Engineering

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D2AN01271E

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