Bivalent AMPA receptor positive allosteric modulators of the bis(pyrimidine) series-Reference-Cited by-同舟云学术

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Bivalent AMPA receptor positive allosteric modulators of the bis(pyrimidine) series

Published:2019 Issue:9 Volume:10 Page:1615-1619
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Nazarova Anna A.¹²³⁴,Sedenkova Kseniya N.¹²³⁴⁵^ORCID,Karlov Dmitry S.¹²³⁴⁶^ORCID,Lavrov Mstislav I.¹²³⁴⁵,Grishin Yuri K.¹²³⁴,Kuznetsova Tamara S.¹²³⁴,Zamoyski Vladimir L.⁵⁷⁸⁴,Grigoriev Vladimir V.¹²³⁴⁵,Averina Elena B.¹²³⁴⁵^ORCID,Palyulin Vladimir A.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Lomonosov Moscow State University

3. 119991 Moscow

4. Russian Federation

5. Institute of Physiologically Active Compounds

6. Center for Computational and Data-intensive Science and Engineering

7. Russian Academy of Sciences

8. Moscow Region

Abstract

Bis(tetrahydroquinazolines) potentiate kainate-induced currents at 10⁻¹²–10⁻⁸ M.

Funder

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00262F

Reference45 articles.

1. AMPA Receptors in the Therapeutic Management of Depression

2. AMPA Receptor Potentiators for the Treatment of CNS Disorders

3. Glutamate Receptor Ion Channels: Structure, Regulation, and Function

4. Ionotropic glutamate receptors

5. Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain

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1. Novel AMPA receptor allosteric modulators of bis(pyrimidine) series: synthesis and SAR evaluation;Mendeleev Communications;2024-01

2. 5-Nitroisoxazoles in SNAr Reactions: A Novel Chemo- and Regioselective Approach to Isoxazole-Based Bivalent Ligands of AMPA Receptors;International Journal of Molecular Sciences;2023-11-09

3. Tetrahydroquinazoline N‐oxide derivatives inhibit reproduction of tick‐borne and mosquito‐borne flaviviruses;Archiv der Pharmazie;2023-05-03

4. Diversity of AMPA Receptor Ligands: Chemotypes, Binding Modes, Mechanisms of Action, and Therapeutic Effects;Biomolecules;2022-12-27

5. Novel Nanomolar Allosteric Modulators of AMPA Receptor of Bis(pyrimidine) Series: Synthesis, Biotesting and SAR Analysis;Molecules;2022-11-26

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