Copper(ii) complexes based on tripodal pyridyl amine derivatives as efficient anticancer agents-Reference-Cited by-同舟云学术

Copper(ii) complexes based on tripodal pyridyl amine derivatives as efficient anticancer agents

Published:2019 Issue:16 Volume:43 Page:6186-6196
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Massoud Salah S.¹²³⁴^ORCID,Louka Febee R.¹²³⁴,Tusa Ada F.¹²³⁴,Bordelon Nicole E.¹²³⁴,Fischer Roland C.⁵⁶⁷⁸,Mautner Franz A.⁹⁶¹⁰⁸,Vančo Ján¹¹¹²¹³¹⁴¹⁵,Hošek Jan¹¹¹²¹³¹⁴¹⁵,Dvořák Zdeněk¹¹¹²¹³¹⁴¹⁵,Trávníček Zdeněk¹¹¹²¹³¹⁴¹⁵^ORCID

Affiliation:

1. Department of Chemistry

2. University of Louisiana at Lafayette

3. Lafayette

4. USA

5. Institut für Anorganische Chemische

6. Technische Universität Graz

7. A-8010 Graz

8. Austria

9. Institut für Physikalische and Theoretische Chemie

10. Graz

11. Division of Biologically Active Complexes and Molecular Magnets

12. Regional Centre of Advanced Technologies and Materials

13. Faculty of Science

14. Palacký University

15. CZ-783 71 Olomouc

Abstract

The in vitro cytotoxicity of a series of chlorido-Cu(ii) complexes based on tripod pyridyl N4-donor derivatives revealed significant-to-moderate cytotoxicity against human cancer cell lines with the best results obtained for [Cu(BQPA)Cl]ClO₄/PF₆ (5-ClO4/PF6) with IC₅₀ values of 4.7–10.8 μM.

Funder

University of Louisiana at Lafayette

Ministerstvo Školství, Mládeže a Tělovýchovy

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ00061E

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