Polypeptide induced perylene probe excimer formation and its application in the noncovalent ratiometric detection of matrix metalloproteinase activity-Reference-Cited by-同舟云学术

Polypeptide induced perylene probe excimer formation and its application in the noncovalent ratiometric detection of matrix metalloproteinase activity

Published:2022 Issue:30 Volume:10 Page:5774-5783
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Gou Xiaoyu¹,Nawaz Muhammad Azhar Hayat²³⁴^ORCID,Liu Chaoyi²,Yang Na²,Ren Jia²,Zhou Huipeng²,Li Yunhui¹⁵,Zhu Jianwei⁵,Han Wenzhao²,Yu Cong²³^ORCID

Affiliation:

1. School of Chemistry and Environmental Engineering, Changchun University of Science and Technology, Changchun 130022, China

2. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

3. University of Science and Technology of China, Hefei 230026, China

4. Interdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University, Islamabad, Lahore Campus, Lahore, 54000, Pakistan

5. Zhongshan Institute of Changchun University of Science and Technology, Zhongshan, 528400, China

Abstract

This research develops a novel ratiometric strategy based on a perylene derivative (PC1) monomer/excimer fluorescence signal transition to detect MMP activity and to screen for potential inhibitors.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Jilin Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB00416J

Reference55 articles.

1. Biosensors and bioassays for determination of matrix metalloproteinases: state of the art and recent advances

2. Matrix Metalloproteinases in Health and Disease