Interaction of spin-labeled HPMA-based nanoparticles with human blood plasma proteins – the introduction of protein-corona-free polymer nanomedicine

Author:

Klepac Damir12345ORCID,Kostková Hana1234,Petrova Svetlana1234ORCID,Chytil Petr1234ORCID,Etrych Tomáš1234ORCID,Kereïche Sami67894,Raška Ivan67894,Weitz David A.10111213ORCID,Filippov Sergey K.1234ORCID

Affiliation:

1. Institute of Macromolecular Chemistry

2. Czech Academy of Sciences

3. 162 06 Prague 6

4. Czech Republic

5. Faculty of Medicine

6. Institute of Biology and Medical Genetics

7. First Faculty of Medicine

8. Charles University

9. 128 01 Prague 2

10. Gordon McKay Laboratory

11. Harvard University

12. Cambridge

13. USA

Abstract

The classical “hard corona–soft corona” paradigm is not valid for HPMA-based nanoparticles.

Funder

Ministerstvo Školství, Mládeže a Tělovýchovy

Grantová Agentura České Republiky

Univerzita Karlova v Praze

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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