Tumor chemical suffocation therapy by dual respiratory inhibitions-Reference-Cited by-同舟云学术

Tumor chemical suffocation therapy by dual respiratory inhibitions

Published:2021 Issue:22 Volume:12 Page:7763-7769
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Xu Yingying¹²³⁴⁵,Guo Yuedong¹²³⁴⁵^ORCID,Chen Lei⁶⁷⁸⁵,Ni Dalong¹²³⁴⁵,Hu Ping¹²³⁴⁵,Shi Jianlin¹²³⁴⁵^ORCID

Affiliation:

1. The State Key Laboratory of High Performance Ceramics and Superfine Microstructures

2. Shanghai Institute of Ceramics

3. Chinese Academy of Sciences

4. Shanghai 200050

5. P. R. China

6. Department of Chemistry

7. Fudan University

8. Shanghai 200433

Abstract

The EDTA- and Rotenone-loaded MPER nanoparticles have been synthesized to suffocate tumor cells to death through inhibiting glycolytic process and mitochondrial oxidative phosphorylation simultaneously in vitro and in vivo.

Funder

National Natural Science Foundation of China

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Science and Technology Commission of Shanghai Municipality

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC00929J

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