An in vitro screening method for probiotics with antidepressant-like effect using the enterochromaffin cell model

Author:

Tian Peijun12345,Zhu Huiyue12345,Zou Renying12345,Kong Qinming12345,Xu Mengshu12345,Zhao Jianxin12345,Zhang Hao12345ORCID,Chen Wei12345ORCID,Wang Gang12345ORCID

Affiliation:

1. State Key Laboratory of Food Science and Technology

2. Jiangnan University

3. Wuxi

4. China

5. School of Food Science and Technology

Abstract

Screening the probiotics with antidepressant-like effects through measuring the bacteria stimulated Tph1 mRNA expression and 5-HTP/5-HT secretion in the enterochromaffin cell model RIN14B.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Collaborative Innovationcenter of Food Safety and Quality Control in Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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