Mixed-mode chromatography-mass spectrometry enables targeted and untargeted screening of carboxylic acids in biological samples-Reference-Cited by-同舟云学术

Mixed-mode chromatography-mass spectrometry enables targeted and untargeted screening of carboxylic acids in biological samples

Published:2022 Issue:10 Volume:14 Page:1015-1022
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Hodek Ondřej¹^ORCID,Argemi-Muntadas Lidia²,Khan Adnan²,Moritz Thomas¹²

Affiliation:

1. Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Linnaeus väg 6, 907 36 Umeå, Sweden

2. Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N, Denmark

Abstract

Mixed-mode chromatography method offers quantification of TCA carboxylates in cells, human plasma, and plants.

Funder

Knut och Alice Wallenbergs Stiftelse

Sveriges Lantbruksuniversitet

Novo Nordisk Fonden

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AY/D1AY02143E

Reference25 articles.

1. ATP synthesis and storage

2. Tumor Cell Metabolism: Cancer's Achilles' Heel

3. Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

4. Determination of carboxylic acids in water by gas chromatography–mass spectrometry after continuous extraction and derivatisation

5. Quantitative GC–MS assay of citric acid from humans and db/db mice blood serum to assist the diagnosis of diabetic nephropathy

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