On-demand reconstitutable hyaluronic acid-doped azathioprine microcrystals effectively ameliorate ulcerative colitis <i>via</i> selective accumulation in inflamed tissues-Reference-Cited by-同舟云学术

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On-demand reconstitutable hyaluronic acid-doped azathioprine microcrystals effectively ameliorate ulcerative colitis via selective accumulation in inflamed tissues

Published:2022 Issue:22 Volume:10 Page:6500-6509
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Lee Juho¹,Oshi Murtada A.²,Kwak Dongmin¹,Kim Hyunwoo¹,Kim Jihyun¹,Hlaing Shwe Phyu¹,Saparbayeva Aruzhan¹,Hwang Seonghwan¹,Jung Yunjin¹^ORCID,Yoo Jin-Wook¹^ORCID

Affiliation:

1. College of Pharmacy, Pusan National University, Busandaehak-ro 63 beon-gil, Geumjeong-gu, Busan, 46241, Republic of Korea

2. College of Pharmacy, Omdurman Islamic University, PO. Box 167, Omdurman, Sudan

Abstract

On-demand reconstitutable hyaluronic acid-doped azathioprine microcrystals showed enhanced therapeutic effects via colitis tissue-selective delivery of azathioprine.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM01137A

Reference44 articles.

1. Curcumin Nanocrystal/pH-Responsive Polyelectrolyte Multilayer Core–Shell Nanoparticles for Inflammation-Targeted Alleviation of Ulcerative Colitis

2. pH-Responsive Alginate-Based Microparticles for Colon-Targeted Delivery of Pure Cyclosporine A Crystals to Treat Ulcerative Colitis

3. Once-daily budesonide MMX in active, mild-to-moderate ulcerative colitis: results from the randomised CORE II study

4. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

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