Exploring the inhibitory mechanism of piceatannol on α-glucosidase relevant to diabetes mellitus

Author:

Jiang Lili1234,Wang Zhen1234,Wang Xiaoyu1234,Wang Shujuan1234,Cao Jun5674,Liu Yong1234ORCID

Affiliation:

1. School of Life and Pharmaceutical Sciences

2. Dalian University of Technology

3. Panjin 124221

4. China

5. Department of Occupational and Environmental Health

6. Dalian Medical University

7. Dalian 116044

Abstract

The non-competitive inhibition of piceatannol on α-glucosidase. A combination of dynamic and static process with one binding site. The involvement of hydrophobic interactions and hydrogen bonding. Dietary recommendations for diabetes or potential antidiabetic drug.

Funder

National Basic Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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