Design, synthesis and biological evaluation of esculetin derivatives as anti-tumour agents
Author:
Affiliation:
1. Laboratory of Pharmaceutical Resource Discovery
2. Dalian Institute of Chemical Physics
3. Chinese Academy of Sciences
4. Dalian
5. China
Abstract
Introduction of a nitrogen containing group as hydrogen bond acceptor is a useful strategy for the structure modification.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA06070B
Reference36 articles.
1. Simple Coumarins and Analogues in Medicinal Chemistry: Occurrence, Synthesis and Biological Activity
2. The Structure and Pharmacological Functions of Coumarins and Their Derivatives
3. Coumarins: Old Compounds with Novel Promising Therapeutic Perspectives
4. New halogenated phenylcoumarins as tyrosinase inhibitors
5. Coumarins permeability in Caco-2 cell model
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