Sulfur–DMSO promoted oxidative coupling of active methylhetarenes with amines: access to amides

Author:

Nguyen Thi Thu Tram1,Duong Viet Dung2,Pham Thi Ngoc Nga1,Duong Quoc Thanh1,Nguyen Thanh Binh2ORCID

Affiliation:

1. Faculty of Basic Sciences, Can Tho University of Medicine and Pharmacy, Vietnam

2. Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Université Paris-Sud, Université Paris-Saclay, 1, av de la Terrasse, 91198 Gif-sur-Yvette, France

Abstract

The sulfur–DMSO couple was found to promote the coupling of active methylhetarenes with amines to yield amides under heating conditions. When 2-methylquinoline was used as the methylhetarene component, the reaction could be catalyzed by Fe, Co and Ni salts.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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