Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands-Reference-Cited by-同舟云学术

Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands

Published:2017 Issue:5 Volume:8 Page:3726-3740
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Griffith Cynthia¹²³⁴,Dayoub Adam S.¹²³⁴,Jaranatne Thamara¹²³⁴,Alatrash Nagham¹²³⁴,Mohamedi Ali¹²³⁴,Abayan Kenneth¹²³⁴,Breitbach Zachary S.¹²³⁴,Armstrong Daniel W.¹²³⁴^ORCID,MacDonnell Frederick M.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry

2. University of Texas at Arlington

3. Arlington

4. USA

Abstract

Yellow foci show time dependent DNA double strand breaks in the nuclei of H358 cells treated with IC₅₀ concentration of [(phen)₂Ru(tatpp)Ru(Phen)₂]Cl₄.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC04094B

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