A multi-functional PEGylated gold(iii) compound: potent anti-cancer properties and self-assembly into nanostructures for drug co-delivery

Author:

Chung Clive Yik-Sham1234,Fung Sin-Ki1234,Tong Ka-Chung1234,Wan Pui-Ki1234,Lok Chun-Nam1234,Huang Yanyu5674,Chen Tianfeng5674,Che Chi-Ming1234

Affiliation:

1. State Key Laboratory of Synthetic Chemistry

2. Department of Chemistry and Chemical Biology Centre

3. The University of Hong Kong

4. China

5. Department of Chemistry

6. Jinan University

7. Guangzhou 510632

Abstract

Amphiphilic gold(iii) porphyrin–PEG conjugates can undergo self-assembly into nanostructures, resulting in promising anti-cancer properties with minimal systemic toxicity. The nanostructures can be employed as nanocarriers for drug co-delivery.

Funder

University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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