Intrinsic folding of the cysteine residue: competition between folded and extended forms mediated by the

Intrinsic folding of the cysteine residue: competition between folded and extended forms mediated by the –SH group

Published:2020 Issue:36 Volume:22 Page:20284-20294
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Goldsztejn Gildas¹²³⁴⁵^ORCID,Mundlapati Venkateswara Rao¹²³⁴⁵^ORCID,Brenner Valérie¹²³⁴⁵^ORCID,Gloaguen Eric¹²³⁴⁵^ORCID,Mons Michel¹²³⁴⁵^ORCID,Cabezas Carlos⁶⁷⁸⁹¹⁰^ORCID,León Iker⁶⁷⁸⁹¹⁰^ORCID,Alonso José Luis⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. LIDYL

2. CEA

3. CNRS

4. Université Paris-Saclay

5. 9119 Gif-sur-Yvette

6. Grupo de Espectrocopía Molecular (GEM)

7. Edificio Quifima

8. Laboratorios de Espectroscopia y Bioespectroscopia

9. Unidad Asociada CSIC

10. Parque Científico UVa

Abstract

A dual microwave and optical spectroscopic study of a capped cysteine amino acid isolated in a supersonic expansion, combined with quantum chemistry modelling, enabled us to access the conformational preferences of Cys embedded in a protein chain.

Funder

Consejería de Educación, Junta de Castilla y León

FP7 Ideas: European Research Council

Ministerio de Ciencia e Innovación

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CP/D0CP03136D

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