2-Amino-6-chloropurine-modified polyamidoamine-mediated p53 gene transfection to achieve anti-tumor efficacy
Author:
Affiliation:
1. Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education
2. School of Life Sciences
3. Jilin University
4. Changchun 130012
5. China
Abstract
The modification of 2-amino-6-chloropurine on polyamidoamine was performed to synthesize a derivative, AP-PAMAM, which was then employed as a carrier for p53 gene delivery to achieve anti-tumor efficacy.
Funder
National Natural Science Foundation of China
Education Department of Jilin Province
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ01870G
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