Amine–carboxylate supramolecular synthon in pharmaceutical cocrystals
Author:
Affiliation:
1. Laboratory of Magnetic Resonance Spectroscopy and Imaging
2. Suzhou Institute of Nano-Tech and Nano-Bionics
3. Chinese Academy of Sciences
4. Suzhou 215123
5. P. R. China
6. CAS Key Laboratory of Nano-Bio Interface
Abstract
Four novel pharmaceutical cocrystals of l-proline were obtained via combined virtual and experimental screening. The results confirm that an amine–carboxylate supramolecular synthon can be used for pharmaceutical cocrystal design.
Funder
Youth Innovation Promotion Association of the Chinese Academy of Sciences
China Postdoctoral Science Foundation
Chinese Academy of Sciences
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CE/C8CE01106K
Reference29 articles.
1. High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids
2. Pharmaceutical cocrystals: walking the talk
3. What is a co-crystal?
4. Building co-crystals with molecular sense and supramolecular sensibility
5. The hydrogen bond
Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Assembly of two palmatine pharmaceutical salts: Changing the motifs and affecting the physicochemical properties by adjusting the position of –COOH on salt formers;Journal of Drug Delivery Science and Technology;2023-09
2. Overcoming the Hydrophobic Nature of Zinc Phenylacetate Through Co-Crystallization with Isonicotinamide;Journal of Pharmaceutical Sciences;2023-07
3. Investigation into the structures and physicochemical properties of multi-component crystals of voriconazole;Chinese Chemical Letters;2023-06
4. Virtual assessment achieved two binary cocrystals based on a liquid and a solid pyridine derivative with modulated thermal stabilities;CrystEngComm;2023
5. Pirfenidone–flavonoid cocrystals with reduced solubility and dissolution rate;CrystEngComm;2023
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3