Design, synthesis and biological profiling of aryl piperazine based scaffolds for the management of androgen sensitive prostatic disorders-Reference-Cited by-同舟云学术

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Design, synthesis and biological profiling of aryl piperazine based scaffolds for the management of androgen sensitive prostatic disorders

Published:2016 Issue:11 Volume:7 Page:2111-2121
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Gupta Sonal¹²³⁴⁵,Pandey Deepti⁶²³⁴,Mandalapu Dhanaraju¹²³⁴,Bala Veenu¹²³⁴⁵,Sharma Vikas⁶²³⁴,Shukla Mahendra⁷²³⁴⁵,Yadav Santosh K.⁶²³⁴,Singh Nidhi⁸²³⁴,Jaiswal Swati⁷²³⁴⁵,Maikhuri Jagdamba P.⁶²³⁴,Lal Jawahar⁷²³⁴⁵,Siddiqi Mohammad I.⁸²³⁴,Gupta Gopal⁶²³⁴,Sharma Vishnu L.¹²³⁴⁵

Affiliation:

1. Medicinal & Process Chemistry Division

2. CSIR-Central Drug Research Institute

3. Lucknow-226031

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

6. Endocrinology Division

7. Pharmacokinetics and Metabolism Division

8. Molecular & Structural Biology Division

Abstract

Twenty-six piperazine derivatives were synthesized and findings revealed that compound9ais promising candidate for management of prostatic disorders.

Funder

Indian Council of Medical Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00426A

Reference39 articles.

1. Depressive symptoms in patients diagnosed with benign prostatic hyperplasia

2. Prostate Cancer, Depression, and Risk of Suicide: Should We Pay More Attention?

3. The economic burden of prostate cancer

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4. Synthesis, biological evaluation, and molecular docking of novel hydroxyzine derivatives as potential AR antagonists;Frontiers in Chemistry;2022-11-03

5. Synthesis and crystal structures of 1-benzoyl-4-(4-nitrophenyl)piperazine and 1-(4-bromobenzoyl)-4-phenylpiperazine at 90 K;Acta Crystallographica Section E Crystallographic Communications;2022-09-22

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