High-precision isotopic analysis of Cu in blood serum via multi-collector ICP-mass spectrometry for clinical investigation: steps towards improved robustness and higher sample throughput-Reference-Cited by-同舟云学术

High-precision isotopic analysis of Cu in blood serum via multi-collector ICP-mass spectrometry for clinical investigation: steps towards improved robustness and higher sample throughput

Published:2017 Issue:3 Volume:32 Page:597-608
ISSN:0267-9477
Container-title:Journal of Analytical Atomic Spectrometry
language:en
Short-container-title:J. Anal. At. Spectrom.

Author:

Lauwens Sara¹²³⁴,Costas-Rodríguez Marta¹²³⁴,Van Vlierberghe Hans⁵⁶³⁴,Vanhaecke Frank¹²³⁴^ORCID

Affiliation:

1. Department of Analytical Chemistry

2. Ghent University

3. BE-9000 Ghent

4. Belgium

5. Department of Gastroenterology and Hepatology

6. Ghent University Hospital

Abstract

A procedure for Cu isolation from serum prior to MC-ICP-MS measurements was developed and applied in a clinical context. The serum Cu isotopic composition does not show diurnal variation.

Funder

Fonds Wetenschappelijk Onderzoek

Bijzonder Onderzoeksfonds

Agentschap voor Innovatie door Wetenschap en Technologie

Publisher

Royal Society of Chemistry (RSC)

Subject

Spectroscopy,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/JA/C6JA00433D

Reference49 articles.

1. High-precision isotopic analysis of essential mineral elements in biomedicine: natural isotope ratio variations as potential diagnostic and/or prognostic markers