One-pot synthesis of aldoximes from alkenes via Rh-catalysed hydroformylation in an aqueous solvent system

Author:

Terhorst M.12345ORCID,Plass C.67895ORCID,Hinzmann A.67895ORCID,Guntermann A.67895ORCID,Jolmes T.12345,Rösler J.12345,Panke D.12345ORCID,Gröger H.67895ORCID,Vogt D.12345ORCID,Vorholt A. J.101112135ORCID,Seidensticker T.12345ORCID

Affiliation:

1. TU Dortmund University

2. Department for Biochemical and Chemical Engineering

3. Laboratory of Industrial Chemistry

4. 44227 Dortmund

5. Germany

6. Bielefeld University

7. Faculty of Chemistry

8. Chair of Industrial Organic Chemistry and Biotechnology

9. 33615 Bielefeld

10. MPI for Chemical Energy Conversion

11. Department of Molecular Catalysis

12. Group Multiphase Catalysis

13. 45470 Mülheim an der Ruhr

Abstract

Aldoxime synthesis directly starting from alkenes was successfully achieved through the combination of hydroformylation and subsequent condensation of the aldehyde intermediate with aqueous hydroxylamine in a one-pot process.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference55 articles.

1. P. Roose , K.Eller , E.Henkes , R.Rossbacher and H.Höke , in Ullmann's Encyclopedia of Industrial Chemistry , Wiley-VCH , Weinheim , 2015 , pp. 1–55

2. S. A. Lawrence , Amines. Synthesis, properties, and applications , Cambridge University Press , Cambridge , 2004

3. Controlling selectivity in the reaction network of aldoxime hydrogenation to primary amines

4. J. F. Liebman and Z.Rappoport , The Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids , John Wiley & Sons Ltd , Chichester, England , 2009

5. Biocatalytic Synthesis of Nitriles through Dehydration of Aldoximes: The Substrate Scope of Aldoxime Dehydratases

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