Ultra-thin membrane filter with a uniformly arrayed nanopore structure for nanoscale separation of extracellular vesicles without cake formation-Reference-Cited by-同舟云学术

Ultra-thin membrane filter with a uniformly arrayed nanopore structure for nanoscale separation of extracellular vesicles without cake formation

Published:2023 Issue:3 Volume:5 Page:640-649
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Kim Daesan¹^ORCID,Lee Jaehyuk²,Kim Boyoung²,Shin Yujin²,Park Jinhong³⁴,Kim Uijoo¹⁵,Lee Minbaek³⁴,Kim Sang Bum⁶,Kim Sunghoon¹⁵

Affiliation:

1. Medicinal Bioconvergence Research Center, Institute for Artificial Intelligence and Biomedical Research, Gangnam Severance Hospital, Yonsei University, Incheon 21983, Korea

2. R&D Center, Metapore Co., Ltd, Advanced Institutes of Convergence Technology, 8F, Suwon 16229, Korea

3. Department of Physics, Inha University, Incheon 22212, Korea

4. The Institute for Basic Science, Inha University, Incheon 22212, Korea

5. College of Pharmacy, College of Medicine, Interdisciplinary Biomedical Center, Gangnam Severance Hospital, Yonsei University, Incheon 21983, Korea

6. College of Pharmacy, Sahmyook University, Seoul 01795, Korea

Abstract

We achieved filtration of an extracellular vesicle (EV) enrichment sample using a nanoporous and ultra-thin membrane structure (NUTS). It allows precise control of the pore size of the membrane via MEMS, enabling accurate size-based isolation.

Funder

Ministry of SMEs and Startups

Yonsei University

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NA/D2NA00227B

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