Chiral derivatization-enabled discrimination and on-tissue detection of proteinogenic amino acids by ion mobility mass spectrometry-Reference-Cited by-同舟云学术

Chiral derivatization-enabled discrimination and on-tissue detection of proteinogenic amino acids by ion mobility mass spectrometry

Published:2022 Issue:47 Volume:13 Page:14114-14123
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Xie Chengyi¹,Chen Yanyan¹,Wang Xiaoxiao¹,Song Yuanyuan¹,Shen Yuting¹,Diao Xin¹,Zhu Lin¹^ORCID,Wang Jianing¹²^ORCID,Cai Zongwei¹^ORCID

Affiliation:

1. State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR, China

2. Institute for Research and Continuing Education, Hong Kong Baptist University, Hong Kong SAR, China

Abstract

The combination of chiral derivatization and ion mobility-mass spectrometry provides the first insights into the separation of 19 pairs of chiral proteinogenic d/l-amino acids in a single run and detection of chiral amino acids in complex samples.

Funder

Science, Technology and Innovation Commission of Shenzhen Municipality

State Key Laboratory of Environmental and Biological Analysis

Hong Kong Baptist University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC03604E

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