Graphene oxide and its nanocomposites with EDTA or chitosan induce apoptosis in MCF-7 human breast cancer

Author:

Doghish Ahmed S.12ORCID,El-Sayyad Gharieb S.34ORCID,Sallam Al-Aliaa M.52ORCID,Khalil Waleed F.6ORCID,El Rouby Waleed M. A.7ORCID

Affiliation:

1. Department of Biochemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City, Cairo 11651, Egypt

2. Department of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, Cairo 11829, Egypt

3. Drug Microbiology Lab, Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt

4. Chemical Engineering Department, Military Technical College (MTC), Egyptian Armed Forces, Cairo, Egypt

5. Biochemistry Department, Faculty of Pharmacy, Ain-Shams University, Abassia, Cairo 11566, Egypt

6. Safety Fuel Cycle Department, Egyptian Nuclear and Radiological Regulatory Authority (ENRRA), Cairo, Egypt

7. Material Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, 62511, Egypt

Abstract

To achieve the advanced anticancer activity of nanocomposites fabricated with graphene oxide (GO), a novel procedure was used during the fabrication of chitosan (CS) or ethylene diamine tetra acetic acid (EDTA).

Funder

Academy of Scientific Research and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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