Jatrorrhizine hydrochloride potentiates the neuraminidase inhibitory effect of oseltamivir towards H7N9 influenza-Reference-Cited by-同舟云学术

Jatrorrhizine hydrochloride potentiates the neuraminidase inhibitory effect of oseltamivir towards H7N9 influenza

Published:2015 Issue:80 Volume:5 Page:64937-64943
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Ye¹²³⁴,Yu Miao⁵²³⁴,Wang Xiaonan⁶⁷⁴,Zhang Xin⁸⁹¹⁰⁴,Wang Xizhu⁵²³⁴,Fang Xuexun⁵²³⁴

Affiliation:

1. School of Life Science

2. Jilin University

3. Changchun 130012

4. China

5. Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education

6. The Second Affiliated Hospital of Mudanjiang Medical College

7. Mudanjiang 157009

8. Department of Pharmacy

9. The First Affiliated Hospital of Jilin University

10. Changchun 130021

Abstract

By analyzing the docking result of the binding position, hydrogen bond interactions, pi–pi interaction, etc., it is likely that jatrorrhizine hydrochloride potentiates the neuraminidase inhibitory effect of oseltamivir towards H7N9 influenza.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA11697J

Reference17 articles.

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3. Resistance of influenza viruses to neuraminidase inhibitors — a review

4. Computational study on new natural polycyclic compounds of H1N1 influenza virus neuraminidase

5. Efficacy of neuraminidase (NA) inhibitors against H1N1 strains of different geographical regions: an in silico approach

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