Modified internucleoside linkages for nuclease-resistant oligonucleotides-Reference-Cited by-同舟云学术

Modified internucleoside linkages for nuclease-resistant oligonucleotides

Published:2021 Issue:1 Volume:2 Page:94-150
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Clavé Guillaume¹²³⁴⁵^ORCID,Reverte Maeva¹²³⁴⁵,Vasseur Jean-Jacques¹²³⁴⁵^ORCID,Smietana Michael¹²³⁴⁵^ORCID

Affiliation:

1. IBMM, Univ. Montpellier

2. CNRS

3. ENSCM

4. Montpellier

5. France

Abstract

This review covers comprehensively the chemical synthesis and hybridization properties of modified internucleoside linkages with reported nuclease resistances and discusses their assets for potential biological applications.

Funder

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CB/D0CB00136H

Reference418 articles.

1. Antisense Oligonucleotides as Therapeutics and their Delivery

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4. RNA Interference (RNAi)-Based Therapeutics: Delivering on the Promise?

5. The therapeutic application of CRISPR/Cas9 technologies for HIV

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