2,4,5-Triaminopyrimidines as blue fluorescent probes for cell viability monitoring: synthesis, photophysical properties, and microscopy applications-Reference-Cited by-同舟云学术

2,4,5-Triaminopyrimidines as blue fluorescent probes for cell viability monitoring: synthesis, photophysical properties, and microscopy applications

Published:2024 Issue:11 Volume:22 Page:2252-2263
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Gonçalves Jorge M.¹²,Gonçalves João N. D.¹³^ORCID,Sousa Luís F.¹²,Rodrigues Lígia R.⁴⁵^ORCID,Correia-de-Sá Paulo⁶^ORCID,Coutinho Paulo J. G.²^ORCID,Castanheira Elisabete M. S.²^ORCID,Oliveira Rui³^ORCID,Dias Alice M.¹^ORCID

Affiliation:

1. CQ-UM — Centre of Chemistry of University of Minho, Department of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal

2. CF-UM-UP — Physics Centre of Minho and Porto Universities and LaPMET (Laboratory of Physics for Materials and Emergent Technologies), Campus de Gualtar, 4710-057, Braga, Portugal

3. CBMA — Centre of Molecular and Environmental Biology, Department of Biology, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal

4. CEB — Centre of Biological Engineering, Department of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal

5. LABBELS – Associate Laboratory, Guimarães, Braga, Portugal

6. Laboratório de Farmacologia e Neurobiologia, Center for Drug Discovery and Innovative Medicines (MedInUP), Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, R. Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal

Abstract

Novel and efficient synthesis of 2,4,5-triaminopyrimidines featuring blue-cyan emission whose biological and computational evaluation highlights cell viability monitoring potential.

Funder

European Regional Development Fund

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00092G

Reference40 articles.

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4. Evaluation of Cell Viability with a Single Fluorescent Probe Based on Two Kinds of Fluorescence Signal Modes

5. Fluorescent Analogs of Biomolecular Building Blocks: Design, Properties, and Applications