The effects of trace metal impurities on Ga-68-radiolabelling with a tris(3-hydroxy-1,6-dimethylpyridin-4-one) (THP) chelator-Reference-Cited by-同舟云学术

The effects of trace metal impurities on Ga-68-radiolabelling with a tris(3-hydroxy-1,6-dimethylpyridin-4-one) (THP) chelator

Published:2019 Issue:64 Volume:9 Page:37214-37221
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cusnir Ruslan¹²³⁴⁵,Cakebread Andrew⁶²⁷⁵,Cooper Margaret S.¹²³⁴⁵,Young Jennifer D.¹²³⁴⁵,Blower Philip J.¹²³⁴⁵^ORCID,Ma Michelle T.¹²³⁴⁵^ORCID

Affiliation:

1. School of Biomedical Engineering and Imaging Sciences

2. King's College London

3. St Thomas' Hospital

4. London SE1 7EH

5. UK

6. Mass Spectrometry Facility

7. London SE1 9NH

Abstract

We have quantified trace metal impurities present in ⁶⁸Ga generator eluant from the widely used Eckert & Ziegler ⁶⁸Ga generator, and measured the effect of these metal impurities on ⁶⁸Ga radiolabelling of a THP chelator.

Funder

Wellcome Trust

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Cancer Research UK

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA07723E

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