Boosting nanomedicine performance by conditioning macrophages with methyl palmitate nanoparticles

Author:

Palomba Roberto1ORCID,di Francesco Martina1,di Francesco Valentina12,Piccardi Federica3,Catelani Tiziano4,Ferreira Miguel1,Palange Anna Lisa1,Decuzzi Paolo1

Affiliation:

1. Laboratory of Nanotechnology for Precision Medicine – Fondazione Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genova, Italy

2. Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genoa, Via Opera Pia, 13, Genoa 16145, Italy

3. Animal Facility – Fondazione Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genova, Italy

4. Electron Microscopy Facility – Fondazione Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genova, Italy

Abstract

Methyl Palmitate Nanoparticles (MPN) boost the tumor accumulation and chemotherapeutic efficacy of nanomedicines by transiently and reversibly inhibiting the phagocytic properties of tissue-resident macrophages.

Funder

H2020 Marie Skłodowska-Curie Actions

Associazione Italiana per la Ricerca sul Cancro

FP7 Ideas: European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

Reference42 articles.

1. Delivering nanomedicine to solid tumors

2. T. J.Anchordoquy , Y.Barenholz , D.Boraschi , M.Chorny , P.Decuzzi , M. A.Dobrovolskaia , Z. S.Farhangrazi , D.Farrell , A.Gabizon and H.Ghandehari , Mechanisms and barriers in cancer nanomedicine: addressing challenges, looking for solutions . ACS Publications , 2017

3. Nanomedicine: current status and future prospects

4. Analysis of nanoparticle delivery to tumours

5. D.Boraschi , P.Italiani , R.Palomba , P.Decuzzi , A.Duschl , B.Fadeel and S. M.Moghimi , Nanoparticles and innate immunity: new perspectives on host defence, Seminars in immunology , Elsevier , 2017 , pp. 33–51

Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3