Electrochemical detection of 7-methylguanosine and DNA-methylation

Author:

do Nascimento Raphael F.12345,Nascimento José A. M.1234,Montenegro João G. S.1234,Nascimento Valberes B.1234,Oliveira Severino Carlos B.1234ORCID

Affiliation:

1. Univesidade Federal Rural de Pernambuco – UFRPE

2. Departamento de Química

3. Recife-PE

4. Brazil

5. Universidade Católica de Pernambuco

Abstract

DNA methylation damage can be detected using a DNA-electrochemical biosensor.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference31 articles.

1. S. C. B. Oliveira , V. C.Diculescu , A. M.Chiorcea-Paquim and A. M.Oliveira-Brett , Electrochemical Biosensors for DNA - Drug Interactions , in Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry , ed. K. Wandelt , Elsevier , Amsterdam , 2017

2. A. M. Chiorcea-Paquim , S. C. B.Oliveira , V. C.Diculescu and A. M.Oliveira-Brett , Applications of DNA-Electrochemical Biosensors in Cancer , in Comprehensive Analytical Chemistry (CAC), Past, Present and Future Challenges of Biosensors and Bioanalytical Tools in Analytical Chemistry: a Tribute to Professor Marco Mascini , ed. I. Palchetti , P. D. Hansen and D. Barceló , Elsevier , Amsterdam , 2017

3. Artificial receptors for the extraction of nucleoside metabolite 7-methylguanosine from aqueous media made by molecular imprinting

4. 7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection.

5. A novel method for detecting 7-methyl guanine reveals aberrant methylation levels in Huntington disease

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