Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents-Reference-Cited by-同舟云学术

Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents

Published:2020 Issue:13 Volume:10 Page:7523-7540
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Alsayed Shahinda S. R.¹²³⁴⁵^ORCID,Lun Shichun⁶⁷⁸⁹¹⁰,Luna Giuseppe¹²³⁴⁵^ORCID,Beh Chau Chun¹¹³¹²⁵^ORCID,Payne Alan D.¹³³⁴⁵,Foster Neil¹¹³¹²⁵,Bishai William R.⁶⁷⁸⁹¹⁰,Gunosewoyo Hendra¹²³⁴⁵^ORCID

Affiliation:

1. School of Pharmacy and Biomedical Sciences

2. Faculty of Health Sciences

3. Curtin University

4. Perth

5. Australia

6. Center for Tuberculosis Research

7. Department of Medicine

8. Division of Infectious Disease

9. Johns Hopkins School of Medicine

10. Baltimore

11. Western Australia School of Mines: Minerals, Energy and Chemical Engineering

12. Bentley 6102

13. School of Molecular and Life Sciences

Abstract

Synthesis and pharmacological evaluation of arylcarboxamide derivatives based on an antimycobacterial indole-2-carboxamide scaffold. The most active compounds demonstrated activities against MDR and XDR M. tb strains.

Funder

Australian Research Council

Curtin University of Technology

National Heart, Lung, and Blood Institute

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA10663D

Reference61 articles.