Synthesis of novel polysubstituted N-benzyl-1H-pyrroles via a cascade reaction of alkynyl Fischer carbenes with α-imino glycine methyl esters-Reference-Cited by-同舟云学术

Synthesis of novel polysubstituted N-benzyl-1H-pyrroles via a cascade reaction of alkynyl Fischer carbenes with α-imino glycine methyl esters

Published:2015 Issue:48 Volume:13 Page:11753-11760
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

de la Cruz Fabiola N.¹²³⁴,López Julio¹²³⁴,Jiménez-Halla J. Óscar C.¹²³⁴,Flores-Álamo Marcos⁵⁶⁴,Tamaríz Joaquín⁷⁸⁴,Delgado Francisco⁷⁸⁴,Vázquez Miguel A.¹²³⁴

Affiliation:

1. Departamento de Química

2. Universidad de Guanajuato

3. 36050 Guanajuato, Gto.

4. Mexico

5. Facultad de Química

6. Universidad Nacional Autónoma de México

7. Departamento de Química Orgánica

8. Escuela Nacional de Ciencias Biológicas-IPN

Abstract

An efficient synthesis of N-benzyl-1H-pyrroles is described by a 1,4-addition/isomerization/ring closure/demetalation process of alkynyl Fischer carbene and iminoester.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01655J

Reference89 articles.

1. Chemistry and Biology of Roseophilin and the Prodigiosin Alkaloids: A Survey of the Last 2500 Years

2. Pyrrole Syntheses by Multicomponent Coupling Reactions

3. Synthesis and Screening for Antiacetylcholinesterase Activity of (1-Benzyl-4-oxopiperidin-3-ylidene)methylindoles and -pyrroles Related to Donepezil

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