Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity-Reference-Cited by-同舟云学术

Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity

Published:2017 Issue:11 Volume:8 Page:7521-7527
ISSN:2041-6520
Container-title:Chem. Sci.
language:en
Short-container-title:Chem. Sci.

Author:

Lukat Peer¹²³⁴⁵,Katsuyama Yohei¹²³⁴⁵,Wenzel Silke¹²³⁴⁵,Binz Tina¹²³⁴⁵^ORCID,König Claudia⁶⁷⁸⁵,Blankenfeldt Wulf⁹¹⁰¹¹⁵¹²^ORCID,Brönstrup Mark¹³¹⁰¹¹⁵^ORCID,Müller Rolf¹²³⁴⁵^ORCID

Affiliation:

1. Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

2. Helmholtz Center for Infection Research and Pharmaceutical Biotechnology

3. Saarland University Campus

4. 66123 Saarbrücken

5. Germany

6. Sanofi Aventis Deutschland

7. Industriepark Höchst

8. 65926 Frankfurt

9. Structure and Function of Proteins

10. Helmholtz Centre for Infection Research

11. 38124 Braunschweig

12. Institute of Biochemistry, Biotechnology and Bioinformatics

13. Department for Chemical Biology

Abstract

The biosynthesis of griselimycins in Streptomyces DSM 40835 and the pathway that stereospecifically converts l-leucine to (2S,4R)-4-methyl-proline are reported by means of biochemical and structural analysis.

Funder

BMBF

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC02622F

Reference20 articles.

1. Global Tuberculosis Report 2015, World Health Organization, Geneva, Switzerland, 2015

2. F. Bénazet , in Antibiotics: Advances in Research : Proceedings of the Congress on Antibiotics Held in Prague, 15–19 June 1964, ed. M. Herold and Z. Gabriel, Butterworths, 1966

Cited by 73 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis, antiproliferative, antituberculosis and in-silico analysis of New Schiff base derivatives of cyclohepta[b]thiophene;Journal of Molecular Structure;2024-08

2. A Review of Antibacterial Candidates with New Modes of Action;ACS Infectious Diseases;2024-07-17

3. Proline Analogues;Chemical Reviews;2024-06-28

4. Computational stabilization of a non-heme iron enzyme enables efficient evolution of new function;2024-04-19

5. Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan;Angewandte Chemie International Edition;2024-02-19