Imaging and therapeutic applications of Zn(ii)-cryptolepine–curcumin molecular probes in cell apoptosis detection and photodynamic therapy

Author:

Qin Qi-Pin12345ORCID,Wei Zu-Zhuang6789,Wang Zhen-Feng12345,Huang Xiao-Ling12345,Tan Ming-Xiong12345ORCID,Zou Hua-Hong1011121314ORCID,Liang Hong1011121314ORCID

Affiliation:

1. Guangxi Key Lab of Agricultural Resources Chemistry and Biotechnology

2. College of Chemistry and Food Science

3. Yulin Normal University

4. 1303 Jiaoyudong Road

5. Yulin 537000

6. School of Pharmaceutical Sciences

7. Sun Yat-sen University

8. Guangzhou 510006

9. P. R. China

10. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources

11. School of Chemistry and Pharmacy

12. Guangxi Normal University

13. 15 Yucai Road

14. Guilin 541004

Abstract

The probes could synergistically promote mitochondrion-mediated apoptosis and enhance tumor therapeutic effects during photodynamic therapy.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangxi Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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