Poly(acrylic acid)-mediated synthesis of cerium oxide nanoparticles with variable oxidation states and their effect on regulating the intracellular ROS level

Author:

Ju Xiaohui1ORCID,Hubalek Kalbacova Marie23ORCID,Šmíd Břetislav1ORCID,Johánek Viktor1ORCID,Janata Martin1,Dinhová Thu Ngan1,Bělinová Tereza4,Mazur Michal5,Vorokhta Maryna6ORCID,Strnad Ladislav7

Affiliation:

1. Department of Surface and Plasma Science, Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic

2. Institute of Pathological Physiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic

3. Faculty of Health Studies, Technical University of Liberec, Liberec, Czech Republic

4. Biomedical Center, Medical Faculty in Pilsen, Charles University, Pilsen, Czech Republic

5. Department of Physical and Macromolecular Chemistry, Faculty of Sciences, Charles University, Prague, Czech Republic

6. Department of Geochemistry, Institute of Rock Structure and Mechanics, Czech Academy of Sciences, Prague, Czech Republic

7. Laboratories of the Geological Institutes, Charles University, Prague, Czech Republic

Abstract

PAA tunes the surface oxidation state of CeO2 and PAA–CeNPs significantly reduce the H2O2-induced intracellular ROS level in the cells.

Funder

Grantová Agentura České Republiky

Ministerstvo Školství, Mládeže a Tělovýchovy

Univerzita Karlova v Praze

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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